Tottenham Hotspur were rampant as Jose Mourinho inflicted a crushing 6-1 defeat on his former club Manchester United at Old Trafford on Sunday.
Arsenal picked up their third win in four games with a 2-1 victory at home to Sheffield United but Leicester City’s 100% start to the season ended with a crash as they were upset 3-0 at home by West Ham United.
Son Heung-min and Harry Kane each scored twice for Spurs while United’s Anthony Martial was sent off in the 28th minute as the home side suffered their joint worst defeat of the Premier League era.
“It is history for Tottenham, history for my boys and I cannot deny it is also history for me,” said a delighted Mourinho, whose side were playing their fourth game in eight days.
Ole Gunnar Solskjaer’s side had taken a second-minute lead through a Bruno Fernandes penalty but Spurs responded quickly, taking advantage of some awful United defending as Tanguy Ndombele and Son put them 2-1 ahead.
United went down to 10 men after Martial was sent off following a clash with Erik Lamela at a corner and then Harry Kane made it 3-1.
Son added his second shortly before the break as United fell to pieces with Harry Maguire and Eric Bailly utterly ineffective in the centre of defence.
A Serge Aurier goal and a Harry Kane penalty in the second half completed a memorable victory for Spurs, which matched United’s 6-1 loss to Manchester City in October, 2011.
Arsenal scored two goals in four minutes to inflict a fourth straight loss on struggling Sheffield United, with Bukayo Saka and Nicolas Pepe on target in the second half.
Saka put the Gunners ahead with a 61st-minute header before substitute Pepe added a second three minutes later.
Irish striker David McGoldrick gave his side hope with a brilliant curling effort in the 84th minute, but Arsenal held firm to continue their progress under Mikel Arteta.
Leicester were on a high after their stunning 5-2 win at Manchester City a week ago, but were brought crashing down to earth by an impressive West Ham.
Michail Antonio headed West Ham into a 14th-minute lead and Pablo Fornals made it 2-0 with a close-range strike 20 minutes later.
Declan Rice hit the underside of the bar for West Ham after a darting solo run from inside his own half before Jarrod Bowen made sure of the win seven minutes from the end after a wonderful pass from Fornals.
Southampton beat an insipid West Bromwich Albion 2-0 with goals either side of halftime from Moussa Djenepo and Oriol Romeu at St Mary’s Stadium.
Pedro Neto’s goal early in the second half earned Wolverhampton Wanderers a 1-0 victory over Fulham at Molineux, leaving the visitors rooted to the bottom of the standings after their fourth successive league defeat.
Champions Liverpool were playing Aston Villa later on Sunday.