Michael Wilson (47) of Scottsdale, Arizona, plunged from an overlook on the South Rim on Monday and died instantly, a National Park Service spokesperson said.
An investigation into the death is under way.
In August, a 19-year-old Canadian man died when he plunged from an outcropping overlooking the canyon, while a 62-year-old American man on a river rafting trip died from a fall into the inner canyon.
Two to three people die from falls in the Grand Canyon every year.
AFP